Basaloid Carcinoma of the Esophagus with Lugol-Voiding Lesions--A Case Report
Shimakawa, T.; Asaka, S.; Shimazaki, A.; Yamaguchi, K.; Usui, T.; Yokomizo, H.; Shiozawa, S.; Yoshimatsu, K.; Katsube, T.; Naritaka, Y.; Fujibayashi, M.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 42(12): 1899-1901
2015
ISSN/ISBN: 0385-0684 PMID: 26805210 Document Number: 680349
Patients with Lugol-voiding lesions of the esophagus are frequently affected with multiple cancers. Basaloid carcinoma of the esophagus is a very rare disease characterized by growth in the submucosal layer that exhibits a submucosal tumor-like shape. There have been some reports that this type of carcinoma is biologically high-grade. We report a case of metachronous squamous cell carcinoma in situ and superficial basaloid carcinoma in the esophagus with Lugol-voiding lesions. A 63-year-old man underwent gastrectomy for gastric cancer at the age of 45 years. The subsequent surveillance endoscopy found a type 0-Ⅱc lesion in the esophagus in 2000. EMR was thus performed. The pathology showed squamous cell carcinoma in situ. Dysplasia was diagnosed based on the Lugol-voiding lesions, and EMR was performed twice. In 2014, a fourth EMR was performed after a high-grade intraepithelial neoplasia was diagnosed. The pathology showed squamous cell carcinoma in situ and a basaloid carcinoma in the lamina propria, T1a-LPM, ly0, v0, pHMX, pVM0. The patient has had no recurrence for approximately 1 year after the fourth EMR.