Cases of Three Patients with Gastric Cancer and Metastasis to the Skeletal Muscle
Sugitani, Y.; Inatomi, O.; Tanabe, R.; Kanda, T.; Sonoda, A.; Hasegawa, H.; Osaki, R.; Imaeda, H.; Ban, H.; Nishida, A.; Shioya, M.; Bamba, S.; Sugimoto, M.; Tsujikawa, T.; Andoh, A.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 42(11): 1419-1421
2015
ISSN/ISBN: 0385-0684 PMID: 26602403 Document Number: 680018
Metastasis to the skeletal muscle from gastric cancer is relatively rare. We report cases of 3 patients undergoing chemotherapy for gastric cancer with metastasis to the skeletal muscle. Case 1: A man in his 70s was diagnosed with advanced gastric cancer (cT4N3M1P0, stage IV), with metastasis to the lung, brain, lymph node, and iliopsoas muscle. Case 2: A man in his 60s was diagnosed with advanced gastric cancer (cT3N3M1P0, stage IV), with metastasis to the brain, lung, lymph node, and iliopsoas muscle. Case 3: A man in his 50s was diagnosed with advanced gastric cancer (cT4N3M1P0, stage IV), with metastasis to the urinary duct, lymph node, back muscle, and iliopsoas muscle. All 3 patients died within 7-8 months after the diagnosis due to progressive disease despite chemotherapy. The prognosis of these 3 patients was significantly poorer than that of patients in our hospital with metastasis not involving the skeletal muscle (p<0.01). Accordingly, metastasis to the skeletal muscle may be an adverse prognostic factor in gastric cancer.