Serotonin and its receptors in the cardiovascular system
Nadeev, A.D.; Zharkikh, I.L.; Avdonin, P.V.; Goncharov, N.V.
Eksperimental'naia i Klinicheskaia Farmakologiia 77(5): 32-37
2014
ISSN/ISBN: 0869-2092 PMID: 25033570 Document Number: 678526
Serotonin in cardiovascular system plays an important role in blood coagulation, allergy, and inflammation, as well as in blood vessel tone regulation. In this review, the mechanisms of serotonin effects upon the cells of blood vessels are considered and the list of main agonists and antagonists is presented. The signaling pathways activated by serotonin and their interaction in normal and pathological states are described.