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Complete response of locally recurrent anorectal cancer to proton beam therapy alone--a case report

Ie, M.; Yamaguchi, T.; Kinugasa, Y.; Sato, S.; Yamakawa, Y.; Kagawa, H.; Tomioka, H.; Shiomi, A.; Fuji, H.; Murayama, S.

Gan to Kagaku Ryoho. Cancer and ChemoTherapy 41(13): 2623-2625

2014

ISSN/ISBN: 0385-0684
PMID: 25596061
Document Number: 677072
We report a case of locally recurrent anorectal cancer treated with proton beam therapy (PBT) alone that led to a clinically complete response. A 70-year-old woman with paraparesis due to infantile paralysis underwent abdominoperineal resection (APR) and D3 lymphadenectomy for anorectal cancer (PERb, type 2, 50×40 mm, muc-tub1, M1a/25 F/5 week) was administered for treatment of the recurred tumor. CT revealed that the tumor disappeared 1 year after PBT, which was defined as complete response. The patient is alive and has not experienced recurrence for 7 years.

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