Advance in studies on long-circulating tumor targeted compound preparations
Li, Q.-P.; Liu, X.-M.; Dai, J.-D.
Zhongguo Zhong Yao Za Zhi 39(3): 402-406
2014
ISSN/ISBN: 1001-5302 PMID: 24946538 Document Number: 676736
Tumor has long been a hard-nut problem in the world medical field. The effect of the conventional drugs is very limited because of the intervention of multiple micro-environmental factors during the occurrence and progression of tumors. With the characteristics of high efficiency, low toxicity and multi-targets synergistic effect, the long-circulating tumor targeted compound preparations show its unique advantages in improving tumor microenvironment and enhancing the therapeutic effect of treatment, thus it has gradually become a hotspot of studies both at home and abroad. Through consulting a great number of professional literatures at home and abroad in recent years, the authors summarized the current studies in vitro and in vive on long-circulating tumor targeted compound preparations in different carriers, in the expectation of providing new ideas and methods for the development of long-circulating tumor targeted compound preparations.