Molecular targeted drugs for soft tissue sarcoma and neuroendocrine tumor
Kato, S.
Nihon Rinsho. Japanese Journal of Clinical Medicine 73(8): 1398-1402
2015
ISSN/ISBN: 0047-1852 PMID: 26281696 Document Number: 685040
Both the soft tissue sarcomas and the neuroendocrine tumors are rare diseases. Therefore the recruiting of these patients was more difficult than other cancer species, and the development of the new therapy for these diseases did not readily advance. However, the identification of driver molecules for each sub-type enabled us to the development of the molecular targeted drugs. As for the GIST, several TKIs are used, but in late years it is found that susceptibility of TKIs varies according to difference in second mutation. In this chapter, the molecular target drug for the soft tissue sarcoma and the neuroendocrine tumor is reviewed.