Thermoradiochemotherapy of inoperable soft-tissue sarcoma

Ivanov, S.M.; Tkachev, S.I.; Bokhian, B.Iu.; Petrovichev, N.N.; Karapetian, R.M.; Machak, G.N.; Nazarenko, A.V.

Voprosy Onkologii 51(3): 350-354

2005


ISSN/ISBN: 0507-3758
PMID: 16279101
Document Number: 591966
Three groups of patients with inoperable soft-tissue sarcoma received preoperative radiotherapy (57), thermoradiotherapy (102) and thermoradiochemotherapy (16) (n=175). Five year recurrence-free survival in group 1 was 37 +/- 7%, group 2 - 48 +/- 6%, and group 3 - 56 +/- 1,7%. Patients survived 5 years and more in group 3 (60 +/- 2%), group 2 - 50 +/- 7%, and group 1 - 44 +/- 8% (p>0.05). Local hyperthermia used in conjunction with radio- and chemoradiotherapy was followed by a significant rise in the rate of complete and partial tumor regression.

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