Hans Selye 70 Years Later: Steroids, Stress Ulcers and H. Pylori
Szabó, S.án.; Selye, H.
Ideggyogyaszati Szemle 67(3-4): 91-94
2014
ISSN/ISBN: 0019-1442 PMID: 26118247 Document Number: 676378
Although Hans Selye is mostly known for his discovery & development of the stress concept, he also introduced the first physiologically sound, structure-activity classification of steroids that was also based on the chemical structure of steroids in 1943. He not only introduced the names of glucocorticoids & mineralocorticoids but discovered the anti- & pro-inflammatory properties, respectively, of these steroids in animal models. Furthermore, he not only described the first stress-induced gastric ulcers in rats (1936) & characterized the first human 'stress ulcers' during the air-raids in London during World War 11 (1943). Thus, Selye was a much more productive & creative scientist than it is generally considered.