Changes of humoral immunity in patients operated for peritonitis
Churpiĭ, I.K.
Klinichna Khirurhiia 2014(2): 14-15
2014
ISSN/ISBN: 0023-2130 PMID: 24923113 Document Number: 674864
The inflammation process course as well as probability of complications occurrence are determined by changes in humoral link of immunity. Positive dynamics of humoral component of the immune answer was trustworthy proved in patients, suffering local peritonitis, what have had witnessed the presence of an active and adequate function of the immune system, which was able to localize the inflammation process. In such course of the disease it is not necessary to conduct additional immune correction. Unfavourable immune profile and its dynamics in patients, suffering diffuse and spreaded peritonitis are determined by the quantity lowering of CD22 without its enhancement on the 3 - 7 day; low level of IgG in conjunction with high level of IgA and IgM (so called "scissors"), what do not change on the 3 - 7 day. The tendency of the IgG level lowering during the treatment constitute an urgent indication for the restorative therapy conduction, using immunoglobulins.