Gelatinous transformation of the bone marrow caused by excessive physical activity and insufficient calorie intake
Andersen, S.A.W.; Salomo, L.; Ralfkiær, E.; Kjeldsen, L.
Ugeskrift for Laeger 176(38)
2014
ISSN/ISBN: 1603-6824 PMID: 25294206 Document Number: 673405
Gelatinous transformation (GT) of the bone marrow is rare and associated with a variety of clinical diseases from malignancy to chronic infection in combination with malnutrition or wasting. A new clinical picture of GT has emerged with excessive physical activity in combination with a voluntary insufficient calorie intake in the young adult male. Overtraining syndrome and systemic inflammation may play a role in the pathogenesis of GT in these patients, but further studies on GT and the effect of training and overtraining on the bone marrow are needed.