Single glucose challenge test procedure for diagnosis of gestational diabetes mellitus: a Jammu cohort study
Sharma, K.; Wahi, P.; Gupta, A.; Jandial, K.; Bhagat, R.; Gupta, R.; Gupta, S.; Singh, J.
Journal of the Association of Physicians of India 61(8): 558-559
2013
ISSN/ISBN: 0004-5772 PMID: 24818340 Document Number: 671346
To elucidate an evidence based Single Glucose Challenge test to diagnose Gestational Diabetes Mellitus (GDM). This study included 500 pregnant women in 16-32 weeks of gestation. They underwent 75g Oral Glucose Challenge test irrespective of the last meal timing and 2 hr venous blood was drawn. After 3 days they underwent 75g OGTT in the fasting state and their 2 hr blood was drawn. Plasma glucose was estimated in both samples by GOD-POD method. GDM was diagnosed with 2hr Plasma glucose (PG) > or = 7.8 mmol/l (> or = 140 mg/dl) based on WHO criteria. The data was analysed by computer software Microsoft excel for windows and epi-info version 6.0, CDC, Atlanta, GA. Among 500 women, 55(11%) were diagnosed as GDM by WHO criteria. It was observed that there was no statistical difference (p > 0.05) between 2 hr PG of GCT and 2 hr PG of WHO recommended method. This Single Glucose Challenge test procedure is cost-effective, evidence based and patient friendly approach to diagnosis Gestational Diabetes Mellitus.