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Management of von Willebrand disease type 3 during pregnancy - 2 cases reports

Inocêncio, G.; Braga, A.; Azevedo, S.; Buchner, G.

European Review for Medical and Pharmacological Sciences 17(21): 2857-2859

2013

ISSN/ISBN: 1128-3602
PMID: 24254552
Document Number: 668899
von Willebrand disease type 3, is an extremely rare condition. It can be severe and potentially life-threatening, particularly in pregnant women during labor and subsequently during early puerperium. Due to its rarity, there is no optimal treatment/management during pregnancy. We describe two cases of pregnant women with von Willebrand disease type 3, and its successful surveillance and treatment with Haemate P FVIII (human plasma-derived von Willebrand Factor-ristocetin co-factor associated with human coagulation factor VIII), during pregnancy, partum and puerperium. Daily prophylaxis with Haemate P FVIII in women with von Willebrand disease type 3, starting 2 hours before caesarean section until the 7th day of puerperium, associated with close analytical and clinical surveillance seems to be a safe clinical option.

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Piao, Y.C.; Lavergne, J.M.; Boyer-Neumann, C.; Schandelong, A.; Alessi, M.C.; Meyer, D. 1993: Arg578Gln mutations in the von Willebrand factor gene in three unrelated cases of type IIB von Willebrand disease Blood Coagulation and Fibrinolysis: An International Journal in Haemostasis and Thrombosis 4(5): 787-789
Mazurier, C.; Meyer, D. 1996: Factor VIII binding assay of von Willebrand factor and the diagnosis of type 2N von Willebrand disease--results of an international survey. On behalf of the Subcommittee on von Willebrand Factor of the Scientific and Standardization Committee of the ISTH Thrombosis and Haemostasis 76(2): 270-274
Rastegar-Lari, G.; Ajzenberg, N.; Ribba, A.S.; Vereycken-Holler, V.; Legendre, P.; Villoutreix, B.; Meyer, D.; Baruch, D. 2001: Defect of heparin binding in plasma and recombinant von Willebrand factor with type 2 von Willebrand disease mutations Thrombosis and Haemostasis 86(6): 1459-1465
Inbal, A.; Kornbrot, N.; Harrison, P.; Randi, A.M.; Sadler, J.E. 1993: Effect of type IIB von Willebrand disease mutation Arg(545)Cys on platelet glycoprotein Ib binding--studies with recombinant von Willebrand factor Thrombosis and Haemostasis 70(6): 1058-1062
Fukui, H.; Okuda, T.; Takase, T.; Mikami, S.; Yoshioka, A.; Fujimura, Y.; Yoshioka, K. 1978: Two cases of atypical von Willebrand's disease with inhibitory effect on von Willebrand factor Nihon Ketsueki Gakkai Zasshi: Journal of Japan Haematological Society 41(5): 897-907
Van Vliet, H.H.D.M.; Kappers-Klunne, M.C.; Leebeek, F.W.G.; Michiels, J.J. 2008: PFA-100 monitoring of von Willebrand factor (VWF) responses to desmopressin (DDAVP) and factor VIII/VWF concentrate substitution in von Willebrand disease type 1 and 2 Thrombosis and Haemostasis 100(3): 462-468
Miller, J.L. 1996: Platelet-type von Willebrand disease Thrombosis and Haemostasis 75(6): 865-869
Nordmann, A. 1998: Mild von type i von Willebrand disease Praxis 87(21): 747-748
Habart, D. 2003: Von Willebrand disease type 2N (Normandy) Vnitrni Lekarstvi 49(4): 253-255
Noller, K.L.; Bowie, E.J.; Kempers, R.D.; Owen, C.A. 1973: Von Willebrand's disease in pregnancy Obstetrics and Gynecology 41(6): 865-872
Gojnic, M.; Fazlagic, A.; Likic, I.; Stefanovic, A.; Vidakovic, S.; Pervulov, M.; Petkovic, S.; Mostic, T.; Miljic, P.; Bogdanovic, A. 2005: New approach of the treatment of von Willebrand's disease during pregnancy Archives of Gynecology and Obstetrics 273(1): 35-38
Coughlan, T.C.; Blagg, J.L.; Abulola, M.; Daly, M.E.; Hampton, K.K.; Makris, M.; Peake, I.R.; Goodeve, A.C. 1999: Null alleles are not a common cause of type 1 von Willebrand disease in the British population Thrombosis and Haemostasis 82(4): 1373-1375
Johnsen, J.M. 2018: Current approaches to pregnancy and childbirth in women with von Willebrand disease Clinical Advances in Hematology and Oncology: H&o 16(4): 254-257
Mammen, E.F. 1975: Von Willebrand's disease--history, diagnosis and management Seminars in Thrombosis and Hemostasis 2(2): 61-84
Gadisseur, A.P.; Vrelust, I.; Vangenechten, I.; Schneppenheim, R.; Van der Planken, M. 2007: Identification of a novel candidate splice site mutation (0874 + 1G > A) in a type 3 von Willebrand disease patient Thrombosis and Haemostasis 98(2): 464-466
Vicente García, V. 1981: Considerations on von Willebrand's disease variants. Report of six cases Sangre 26(1): 76-84
Martinić, P. 1980: Von Willebrand's disease. Laboratory diagnosis and a report of 2 cases Medicinski Pregled 33(9-10): 411-417
Hilbert, L.; Federici, A.B.; Baronciani, L.; Dallagiovanna, S.; Mazurier, C. 2004: A new candidate mutation, G1629R, in a patient with type 2A von Willebrand's disease: basic mechanisms and clinical implications Haematologica 89(9): 1128-1133
Castaman, G.; Eikenboom, J.C.; Bertina, R.M.; Rodeghiero, F. 1999: Inconsistency of association between type 1 von Willebrand disease phenotype and genotype in families identified in an epidemiological investigation Thrombosis and Haemostasis 82(3): 1065-1070
Francesconi, M.A.; Deana, R.; Girolami, A.; Pontara, E.; Casonato, A. 1993: Platelet aggregation induced by plasma from type IIB von Willebrand's disease patients is associated with an increase in cytosolic Ca2+ concentration Thrombosis and Haemostasis 70(4): 697-701