The efficacy of antihypertension drugs and their combinations in the non-treated hypertension
Ruksin, V.V.; Grishin, O.V.; Chiritso, M.M.
Meditsina Truda i Promyshlennaia Ekologiia 5: 7-11
2013
ISSN/ISBN: 1026-9428 PMID: 24000722 Document Number: 668590
In case of non-treated hypertension several medications and their combinations were studied (captopril, and moxonidine as such, captopril + nifedipine, captopril + moxonidine). Moxonidine to be more effective in patients with the prevalence of the sympathetic tone, captopril in patients without increased sympathetic activity. At a combination of captopril + nifedipine efficiency of therapy was reduced, and at a combination moxonidine + nifedipine - increased. Beyond that administration of captopril + nifedipine possessed more side effects, as to compare with the moxonidine + nifedipine.