Conformationally stable segments in helical structures of polypeptide chains of proteins and their role in high level structures formation
Batianovskiĭ, A.V.; Namiot, V.A.; Filatov, I.V.; Moldaver, M.V.; Anashkina, A.A.; Tumanian, V.G.; Esipova, N.G.; Volotovskiĭ, I.D.
Biofizika 58(6): 1069-1073
2013
ISSN/ISBN: 0006-3029 PMID: 25486767 Document Number: 667245
In the work the arguments are presented in favor of the idea on the role of conformationally stable oligo-peptides in specific long-distance interactions in phenomena of molecular recognition during various biological processes. Original authors' and literature data are taken into account. The examples of conformationally stable short oligopeptides participation in alpha-helix and collagen type structures formation are given simultaneously with theoretical approaches. The conformationally stable oligopeptides obtained in the course of PDB bank analysis are discussed. The role of amino acids sequence in collagen helix formation is shown.