Human sperm chromatin damage and its determination: an update
Zhao, K.; Xiong, C-Liang.
Zhonghua Nan Ke Xue 19(5): 460-463
2013
ISSN/ISBN: 1009-3591 PMID: 23757973 Document Number: 666709
Human sperm chromatin damage is one of the common reasons for reduced male reproductive capacity, which is influenced by genetics, environment, lifestyle and other factors, as well as associated with male infertility and habitual abortion. Along with deeper insights into the structure and function of sperm chromatin, improvement and promotion of detection technology for its integrity, and wider application of assisted reproductive technology, sperm DNA damage has been recognized as an important new indicator for the evaluation of sperm quality, and has a great clinical significance in the assessment of male fertility and selection of assisted reproductive technology.