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Ocular blood flow assessment in normal subjects and in patients with hyperglycemia based on the results of ultrasonic examination in experiment

Neroev, V.V.; Kiseleva, T.N.; Riabina, M.V.; Okhotsimskaia, T.D.; Zolotykh, O.V.

Vestnik Oftalmologii 129(2): 14-18

2013

ISSN/ISBN: 0042-465X
PMID: 23808174
Document Number: 666518
Scheme of ocular blood flow in rats was developed and main blood flow parameters were studied using color Doppler mapping, energetic mapping and impulse Doppler ultrasonography. Features of ocular blood flow changes are revealed in experimental model of streptozotocin induced diabetes mellitus during 12 months of follow-up. Inferior ophthalmic artery showed the most significant changes. Decrease of all parameters of blood flow velocity was found in central retinal artery, central retinal vein and in posterior long ciliary arteries. Increase of resistance index was observed during the entire follow-up period. Revealed data show development of hemodynamic changes before clinical signs of retina damage ip rats with hyperglycemia.

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