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Successful management using laparoscopic splenectomy for splenomegaly and thrombocytopenia caused by oxaliplatin-based chemotherapy for advanced rectal cancer

Koike, N.; Ohshima, Y.; Takeuchi, T.; Arita, S.; Shinozaki, E.

Gan to Kagaku Ryoho. Cancer and ChemoTherapy 40(6): 815-817

2013

ISSN/ISBN: 0385-0684
PMID: 23863666
Document Number: 665785
We report a case of advanced rectal cancer treated with chemotherapy, for which laparoscopic splenectomy had been effective for thrombocytopenia. A 56-year-old man suffered from advanced rectal cancer with multiple lung metastases. He underwent Hartmann's procedure and received chemotherapy with FOLFOX and FOLFIRI with bevacizumab. After 3 years and 2 months, he also suffered from splenomegaly and thrombocytopenia. Laparoscopic splenectomy produced and increased the thrombocyte count, allowing for a restart of chemotherapy. Oxaliplatin-based chemotherapy might produce hepatic sinusoid injury and induce splenomegaly owing to portal hypertension. Laparoscopic splenectomy seemed to be useful for treating thrombocytopenia, and allowed the continuation of chemotherapy.

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Hiramoto, K.; Kuroki, M.; Nakano, E.; Kanno, N.; Matsumura, Y.; Miura, A.; Kikuchi, Y.; Hirakawa, H. 2011: Successful management with partial splenic embolization (PSE) of splenomegaly and thrombocytopenia caused by oxaliplatin-based chemotherapy for advanced colorectal cancer Gan to Kagaku Ryoho. Cancer and ChemoTherapy 38(5): 835-839
Takahashi, H.; Ishikawa, T.; Iwata, N.; Baba, H.; Masuda, T.; Okazaki, S.; Matsuyama, T.; Ishiguro, M.; Kobayashi, H.; Iida, S.; Uetake, H.; Sugihara, K. 2013: A case of advanced rectal cancer treated with leucovorin, fluorouracil, and oxaliplatin plus panitumumab preoperative chemotherapy Gan to Kagaku Ryoho. Cancer and ChemoTherapy 40(12): 1953-1955
Katayose, Y.; Nakagawa, K.; Onogawa, T.; Yoshida, H.; Motoi, F.; Naitoh, T.; Rikiyama, T.; Egawa, S.; Unno, M. 2011: A case of hypersensitivity reaction to reintroduced-oxaliplatin at the second course of oxaliplatin-based chemotherapy after neoadjuvant chemotherapy for liver metastases from colon cancer Gan to Kagaku Ryoho. Cancer and ChemoTherapy 38(13): 2651-2653
Lygidakis, N.J.; Patil, A.; Giannoulis, K.; Fukuda, T.; Kumar, R. 2010: Laparoscopic hyperthermic intraperitoneal chemotherapy as adjuvant modality following radical surgery for advanced rectal cancer a new look to an old problem Hepato-Gastroenterology 57(97): 73-75
Neduka, H.; Munemoto, M.; Ojima, T.; Earashi, M.; Fujii, H.; Nonomura, A. 2016: Highly Advanced Gastric Cancer Leading to Immediate Perforation on day Three of Chemotherapy with S-1 plus Oxaliplatin Gan to Kagaku Ryoho. Cancer and ChemoTherapy 43(12): 1939-1941
Qian, J.; Qin, S.-k.; Mei, J.-f.; Chen, Y.-x.; Shao, Z.-j.; He, Z.-m. 2004: Oxaliplatin plus capecitabine as a second line chemotherapy for patients with advanced gastric cancer Zhonghua Zhong Liu Za Zhi 26(12): 746-748
Terashima, T.; Kawamoto, S.; Maekawa, K.; Kuroki, N. 2017: A Successful Treatment for Stage IIi c Gastric Cancer with Low Cardiac Function Using S-1 plus Oxaliplatin(SOX)as a Neoadjuvant Chemotherapy Gan to Kagaku Ryoho. Cancer and ChemoTherapy 44(12): 1892-1894
Lu, J.-w.; Zhou, Z.-f.; Yin, B.-j.; Liu, D.-l.; Feng, J.-f.; Zhu, L.-j.; Pan, L.-x. 2005: Chronomodulated chemotherapy of oxaliplatin, 5-fluorouracil and folinic acid for advanced gastric cancer Zhonghua Zhong Liu Za Zhi 27(11): 695-697
Suematsu, Y.; Yamagishi, S.; Saito, H.; Takahashi, M.; Nakayama, M.; Fukabori, M.; Morita, A.; Wakabayashi, K.; Itoh, Y. 2016: A Case of Advanced Gastric Cancer with a Pathological Complete Response after Neoadjuvant Chemotherapy(S-1/Oxaliplatin) Gan to Kagaku Ryoho. Cancer and ChemoTherapy 43(12): 2225-2227
Yabe, N.; Murai, S.; Shimizu, H.; Kitasato, K.; Yoshikawa, T.; Oto, I.; Nakadai, J.; Hasegawa, H.; Kitagawa, Y. 2013: Recurrent rectal cancer with multiple liver and lung metastases treated effectively with oxaliplatin and capecitabine plus bevacizumab chemotherapy-a case report Gan to Kagaku Ryoho. Cancer and ChemoTherapy 40(12): 1834-1836
Nakayasu, Y.; Yoshimatsu, K.; Yokomizo, H.; Osawa, G.; Yano, Y.; Nakayama, M.; Sakuma, A.; Yamaguchi, K.; Shiozawa, S.; Shimakawa, T.; Katsube, T.; Naritaka, Y. 2013: Two cases of locally advanced colorectal cancer curatively resected after neoadjuvant chemotherapy with 5-fluorouracil, leucovorin, and oxaliplatin plus panitumumab Gan to Kagaku Ryoho. Cancer and ChemoTherapy 40(12): 2029-2031
Hatano, S.; Matsuzawa, T.; Chika, N.; Tajima, Y.; Watanabe, Y.; Fukuchi, M.; Baba, H.; Kumagai, Y.; Ishibashi, K.; Mochiki, E.; Ishida, H. 2014: Is PCi effective in predicting prognosis in the era of oxaliplatin-based chemotherapy in stage IV colorectal cancer with peritoneal dissemination ? Gan to Kagaku Ryoho. Cancer and ChemoTherapy 41(12): 1692-1694
Guadagni, S.; Gianardi, D.ée.; Morelli, L. 2019: Hand-Assisted Splenic Bed Laparoscopic Splenectomy for Massive Splenomegaly Secondary to Portal Hypertension and Liver Cirrhosis American Surgeon 85(5): E271-E272
Hamano, G.; Ikebe, T.; Mayumi, K.; Takemura, M.; Hori, T.; Nishioka, T. 2013: Successful treatment of a patient using mFOLFOX6 after laparoscopic surgery for rectal cancer with peritoneal dissemination Gan to Kagaku Ryoho. Cancer and ChemoTherapy 40(7): 951-954
Imaizumi, H.; Ishibashi, K.; Okada, N.; Tajima, Y.; Amano, K.; Hatano, S.; Kuwabara, K.; Sobajima, J.; Ishiguro, T.; Ohsawa, T.; Kumamoto, K.; Kumagai, Y.; Haga, N.; Ishida, H. 2012: Clinical outcomes in refractory colorectal cancer patients with wild-type K-ras treated with bevacizumab and oxaliplatin-based chemotherapy as a first-line treatment Gan to Kagaku Ryoho. Cancer and ChemoTherapy 39(12): 2185-2188
Yoshida, T.; Morohashi, H.; Ichinohe, D.; Yoshida, E.; Okano, K.; Nagase, H.; Akasaka, H.; Jin, H.; Miura, T.; Sakamoto, Y.; Hakamada, K. 2016: A Case of Laparoscopic Surgery for Rectal Cancer with Synchronous Lung Metastases after Chemotherapy Gan to Kagaku Ryoho. Cancer and ChemoTherapy 43(12): 2320-2322
Yagi, Y.; Iiai, T.; Saitou, K.; Kameyama, H.; Nogami, H.; Umezu, H.; Hatakeyama, K. 2011: A case of advanced rectal cancer resected successfully after preoperative XELOX chemotherapy Gan to Kagaku Ryoho. Cancer and ChemoTherapy 38(7): 1221-1224
Rosique-Robles, D.; Vicent Verge, J.M.; Borrás-Blasco, J.; Giner-Marco, V.; Casterá, E.; Galan-Brotons, A.; Abad, J. 2007: Successful desensitization protocol for hypersensitivity reactions caused by oxaliplatin International Journal of Clinical Pharmacology and Therapeutics 45(11): 606-610
Zhou, D.-l.; Zheng, C.-z.; Li, J.-h.; Yin, K.; Ke, C.-w.; Liu, H.-t.; Hu, X.-g.; Chen, D.-l.; Zhang, D.-y. 2009: Application of neoadjuvant chemotherapy in laparoscopic gastrectomy for advanced gastric cancer Zhonghua Wei Chang Wai Ke Za Zhi 12(2): 126-129
Tonooka, T.; Takiguchi, N.; Nabeya, Y.; Takayama, W.; Ikeda, A.; Soda, H.; Chiba, S.; Hoshino, I.; Arimitsu, H.; Yanagibashi, H.; Chibana, T.; Teranaka, R.; Nagata, M. 2017: A Case of Locally Advanced Rectal Cancer Invading Posteriorly Adjacent to Sacrum Resected by Laparoscopic Low Anterior Resection Gan to Kagaku Ryoho. Cancer and ChemoTherapy 44(12): 1862-1864