Fate of leucine in the biosynthesis of bakuchiol, a meroterpene from Psoralea corylifolia
Banerji, A.; Chintalwar, G.J.
Indian Journal of Biochemistry and Biophysics 26(6): 394-396
1989
ISSN/ISBN: 0301-1208 PMID: 2632364 Document Number: 665
Significant incorporations of labelled leucine, valine and isovaleric acid into the meroterpene, bakuchiol (1) isolated from the medicinal plant, Psoralea corylifolia have been observed. Degradation experiments show that labels from these substrates find their way into both phenylpropane derived as well as terpenic part of 1 thereby indicating that none of the known pathways is operative in the case of 1. It is suggested that these substrates are metabolised to CO2 which is then incorporated into 1.
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