To explore the safety testing evaluation index of breast-feeding by hepatitis B-positive mothers
Zhang, W-Ping.; Shi, H-Ying.; Li, C-Bin.; Li, Q-Hong.; Du, P.
Zhonghua Shi Yan he Lin Chuang Bing du Xue Za Zhi 27(3): 202-203
2013
ISSN/ISBN: 1003-9279 PMID: 24319957 Document Number: 664947
To explore the safety testing evaluation index of breast-feeding by hepatitis B-positive mothers. HBV DNA from serum and breast milk of 252 hepatitis B-positive mothers were detected with the real-time quantitative PCR. The total positive rate of HBV DNA in serum had no difference with that in breast milk in hepatitis B-positive mothers (P > 0.05). The positive rate of HBV DNA in serum and breast milk of positive HBeAg were significantly higher than that of hepatitis B-positive mothers with negative HBeAg (P < 0.01). To detecte HBeAg and HBV DNA in serum and breast milk have important significance for guiding of breast feeding of hepatitis B-positive mothers.