Effects of bemethyl, ethomersol, and yakton on the liver regeneration after partial hepatectomy
Gaĭvoronskaia, V.V.; Okovityĭ, S.V.; Shustov, E.B.; Smirnov, A.V.
Eksperimental'naia i Klinicheskaia Farmakologiia 63(5): 34-36
2000
ISSN/ISBN: 0869-2092 PMID: 11109523 Document Number: 6647
It is experimentally demonstrated for the first time that the new drugs bemithyl, etomerzol, and yakton are capable of accelerating the process of liver regeneration following partial hepatectomy. The drugs produce a hasty gain in the mass of liver, increase in the content of nucleic acids and glycogen, and improve the functional state, as manifested by a decrease in the blood bilirubin and a reduction in the hexenal sleep duration. Bemithyl, etomerzol, and yakton produce a positive effect upon the liver morphology and the intracellular regeneration process. The repair activity of the new drugs exceeds that of a combination of the well-known regeneration stimulants riboxin and potassium orotate, representing derivatives of purine and pyrimidine bases.
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