Effectiveness of synthetic antioxidants in treatment of patients with peptic ulcer (an open randomized controlled trial)
Podoprigorova, V.G.; Khibin, L.S.; Kozlov, N.B.; Barsel', V.A.
Klinicheskaia Meditsina 77(3): 32-35
1999
ISSN/ISBN: 0023-2149 PMID: 10234944 Document Number: 6644
Two randomized groups of ulcer patients were compared. 102 patients of group 1 were treated with synthetic antioxidants (dibunol, probucol, emoxipine), while 100 patients of group 2 received a conventional treatment. Treatment results in group 1 appeared better: shortening of ulcer scarring, higher percentage of ulcer healing for 2 and 4 weeks, fall in the number of relapses during the first year of the follow-up, improvement in lipid peroxidation and antioxidant activity.
Document emailed within 1 workday
Related Documents
Lin, H.J.; Chan, C.Y.; Lee, F.Y.; Huang, Z.C.; Lee, C.H.; Lee, S.D. 1991: Endoscopic injection to arrest peptic ulcer hemorrhage: a prospective, randomized controlled trial; preliminary results Hepato-Gastroenterology 38(4): 291-294Piñero, R.; Ramon Poleo, J.; Urrestarazo, M.; Serrano, N.; Olavarría, R. 1995: Changes in the natural history of peptic ulcer after Helicobacter pylori eradication. Randomized, double-blind, placebo controlled trial. Follow-up of 44 months G.E.N 49(1): 50-54
Che, T.-t.; Wang, X.; Liu, Y.-y.; Tian, H.-m.; Yang, G.-y.; Xu, M.; Xiao, C.-q.; Zhu, L.ü-y.; Lü, X.-f.; Yu, H.-l.; Zhang, X.-x.; Ren, Y. 2011: The efficacy and safety of recombinant human insulin injection in the treatment of diabetic patients:a multicenter, randomized, controlled and open-labeled clinical trial Zhonghua Nei Ke Za Zhi 50(1): 23-26
Yamada, S.; Wongwanakul, P. 2012: Randomized controlled trial of high dose bolus versus continuous intravenous infusion pantoprazole as an adjunct therapy to therapeutic endoscopy in massive bleeding peptic ulcer Journal of the Medical Association of Thailand 95(3): 349-357
Klement, E.; Pitché, P.; Kendjo, E.; Singo, Aétina.; D'Almeida, Séphane.; Akouete, F.; Akpaloo, Y.; Tossa, K.; Prince-Agbodjan, S.; Patassi, A.; Caumes, E. 2014: Effectiveness of co-trimoxazole to prevent Plasmodium falciparum malaria in HIV-positive pregnant women in sub-Saharan Africa: an open-label, randomized controlled trial Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 58(5): 651-659
Mansoor, L.E.; Abdool Karim, Q.; Mngadi, K.T.; Dlamini, S.; Montague, C.; Nkomonde, N.; Mvandaba, N.; Baxter, C.; Gengiah, T.N.; Samsunder, N.; Dawood, H.; Grobler, A.; Frohlich, J.A.; Abdool Karim, S.S. 2014: Assessing the implementation effectiveness and safety of 1% tenofovir gel provision through family planning services in KwaZulu-Natal, South Africa: study protocol for an open-label randomized controlled trial Trials 15: 496
Hammond, A.; Andus, T.; Gierend, M.; Ecker, K-Walter.; Scholmerich, J.; Herfarth, H. 2004: Controlled, open, randomized multicenter trial comparing the effects of treatment on quality of life, safety and efficacy of budesonide foam and betamethasone enemas in patients with active distal ulcerative colitis Hepato-Gastroenterology 51(59): 1345-1349
Loginov, A.S.; Zverkov, I.V.; Kondashova, Z.D.; Sokolova, G.N.; Minushkin, O.N. 1992: The treatment of patients with duodenal peptic ulcer with a synthetic prostaglandin E2 analog (enprostil) Terapevticheskii Arkhiv 64(8): 77-79
Pajareya, K.; Chadchavalpanichaya, N.; Painmanakit, S.; Kaidwan, C.; Puttaruksa, P.; Wongsaranuchit, Y. 2004: Effectiveness of physical therapy for patients with adhesive capsulitis: a randomized controlled trial Journal of the Medical Association of Thailand 87(5): 473-480
Cañete, R.; Rivas, D.E.; Escobedo, A.A.; González, M.E.; Almirall, P.; Brito, K. 2010: A randomized, controlled, open-label trial evaluating the efficacy and safety of chloroquine in the treatment of giardiasis in children West Indian Medical Journal 59(6): 607-611
Tseng, G.Y.; Lin, H.J.; Lin, H.Y.; Perng, C.L.; Lee, F.Y.; Lo, W.C.; Chang, F.Y.; Lee, S.D. 1999: The influence of intravenous omeprazole on intragastric pH and outcomes in patients with peptic ulcer bleeding after successful endoscopic therapy--a prospective randomized comparative trial Hepato-Gastroenterology 46(28): 2183-2188
Jula, A.; Marniemi, J.; Huupponen, R.; Virtanen, A.; Rastas, M.; Rönnemaa, T. 2002: Effects of diet and simvastatin on serum lipids, insulin, and antioxidants in hypercholesterolemic men: a randomized controlled trial JAMA 287(5): 598-605
Kayasseh, L.; Gyr, K.; Keller, U.; Stalder, G.A. 1980: Somatostatin and cimetidine in peptic ulcer hemorrhage. a randomized controlled study Zeitschrift für Gastroenterologie 18(6): 342-343
Kumar, S.; Golla, R.; Bhalla, A.; Sharma, N.; Varma, S. 2020: 0.9% Saline v/s Ringer's Lactate for fl uid resuscitation in adult sepsis patients in emergency medical services: An open label Randomized Controlled trial Journal of the Association of Physicians of India 68(1): 87
Onwujekwe, O.; Mangham-Jefferies, L.; Cundill, B.; Alexander, N.; Langham, J.; Ibe, O.; Uzochukwu, B.; Wiseman, V. 2015: Effectiveness of Provider and Community Interventions to Improve Treatment of Uncomplicated Malaria in Nigeria: a Cluster Randomized Controlled Trial Plos one 10(8): E0133832
Chittumma, P.; Kaewkiattikun, K.; Wiriyasiriwach, B. 2007: Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial Journal of the Medical Association of Thailand 90(1): 15-20
Hirunwiwatkul, P.; Wachirasereechai, K. 2005: Effectiveness of combined antibiotic ophthalmic solution in the treatment of hordeolum after incision and curettage: a randomized, placebo-controlled trial: a pilot study Journal of the Medical Association of Thailand 88(5): 647-650
Maliukh, L.S.; Kriklivets, I.I.; Iatskiv, M.V. 1986: Effectiveness of imodium in the treatment of patients with peptic ulcer and chronic gastroduodenitis associated with functional intestinal disorders Klinicheskaia Meditsina 64(3): 96-99
Nakamura, M.; Tahara, T.; Shiroeda, H.; Matsunaga, K.; Otsuka, T.; Yonemura, J.; Shibata, T.; Arisawa, T. 2015: The effect of short-term proton pump inhibitor plus anti-ulcer drug on the healing of endoscopic submucosal dissection-derived artificial ulcer: a randomized controlled trial Hepato-Gastroenterology 62(137): 219-224
Pajareya, K.; Chadchavalpanichaya, N.; Timdang, S. 2003: Effectiveness of an elastic knee sleeve for patients with knee osteoarthritis: a randomized single-blinded controlled trial Journal of the Medical Association of Thailand 86(6): 535-542