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The development of secondary immunodeficiency in body when exposed to the effect of xenobiotics with immunosuppressive activity

Kalinina, O.V.; Zheleznova, A.D.; Panfilova, T.V.; Frolov, B.A.

Gigiena i Sanitariia 3: 73-75

2012

ISSN/ISBN: 0016-9900
PMID: 23088138
Document Number: 663368
The State Education Institution of Higher professional education "The Orenburg State Medical Academy of Federal Agency in Public Health and Social Development". In the experiment on mice (CBA x C57Bl6) F1 and Wistar rats is shown the protective effect of triterpenoid plant--miliatsina (3-beta-methoxy-delta18-oleanena) in relation to the humoral immune response and clearance macrophage function hepatic xenobiotic conditions of use--methotrexate. The results define the term as used miliatsina immunoprotector with adverse effects on the body of environmental and industrial chemical factors that form the secondary immunodeficiency.

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