Immunomodulatory effects of alcbholic and hydroalcoholic extracts of Moringa olifera Lam leaves
Banji, O.J.F.; Banji, D.; Kavitha, R.
Indian Journal of Experimental Biology 50(4): 270-276
2012
ISSN/ISBN: 0019-5189 PMID: 22611915 Document Number: 659646
Effects of 50, 100 and 200 mg/kg body weight of the alcoholic and hydro-alcoholic extract of leaves of M. olifera were studied on various immune paradigms like delayed type hypersensitivity reaction using SRBC as an antigen, determination of antibody titer, neutrophil adhesion test as an indicator for neutrophil index, total leucocyte count in cyclophosphamide induced immunosuppressed animals and carbon clearance assay as a measure of phagocytic activity. Hydro-alcoholic extract of M. olifera substantially enhanced cellular immune response, humoral immune response, neutrophil index and phagoctic activity in doses of 100 and 200 mg/kg body weight. The ethanolic extract (200 mg/kg body weight) was efficient in improving immune response. The results suggest that M. olifera has a significant role to play as an immune stimulator.