Surgical resection and S-1 administration for the treatment of hepatocellular carcinoma
Furukawa, K.; Kawamoto, K.; Hama, N.; Akita, H.; Wada, H.; Kobayashi, S.; Marubashi, S.; Eguchi, H.; Umeshita, K.; Doki, Y.; Mori, M.; Nagano, H.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 39(12): 1994-1996
2012
ISSN/ISBN: 0385-0684 PMID: 23267954 Document Number: 656752
A 57-year-old man was admitted to our hospital for hepatocellular carcinoma (HCC). He underwent right hepatectomy with preoperative adjuvant transcatheter arterial chemoembolization. A follow-up computed tomography scan revealed a single pulmonary metastasis. After 2 courses of S-1 administration, he underwent left lower lobectomy, and a pathological specimen taken at the time was diagnosed as pulmonary metastasis of HCC. Although adjuvant chemotherapy with S-1 resulted in relapse-free survival for 2 years after pulmonary resection, he was found to have recurrence of liver cancer and underwent partial hepatectomy. This case report suggests that surgical resection and S-1 administration would be a useful treatment option for hepatocellular carcinoma with distant metastasis.