Hydration of the compact and extended forms of pFh fragments from IgG3 Kuc and sur
Tishchenko, V.M.
Biofizika 56(1): 5-6
2011
ISSN/ISBN: 0006-3029 PMID: 21442878 Document Number: 655695
It has been shown using scanning microcalorimetry and densitometry that partial specific heat and specific partial volume of two pFh fragments of IgG3 increase during the decay of its tertiary structure, the secondary structure, the double poly-L-proline helix, being unchanged. This effect may be explained by a high degree of hydration, which increases on globule decompactization due to increased accessibility of peptide groups of the helix to solvent.