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Long-term efficacy and safety of a generic atorvastatin in usual clinical care setting

Ong, L.M.; Punithavathi, N.; Lena, Y.L.L.; Mahanim, O.; Leekha, S.; Sia, K.K.; Yuhanis, Y.; Khor, B.T.; Adlina, B.; Hema, P.; Ch'ng, S.K.; Letchuman, G.R.; Chia, W.K.; Sim, K.H.; Chin, W.M.; Ong, T.K.; Ang, C.K.; Liew, H.B.; Annuar, R.; Fong, Y.Y.; Yew, K.L.; Yoon, C.K.; Leong, B.; Chandran, K.; Ang, C.L.; Suriani, S.; Koay, B.S.; Ahmad, R.; Ngau, Y.Y.; Narul, A.; Lee, T.S.; Ang, S.F.; Jeyabalan, T.

Medical Journal of Malaysia 66(3): 214-219

2011

ISSN/ISBN: 0300-5283
PMID: 22111443
Document Number: 651286
A multicentre study was conducted to assess the long term efficacy and safety of a generic atorvastatin in the treatment of primary hypercholesterolaemia. Eighty five patients who received 10mg or 20 mg of atorvastatin for 8 weeks depending on target cholesterol goal were followed up by their own physicians and had final evaluation at 52 weeks. Reduction in mean low density Lipoprotein (LDL-C) was 36.5%, 37.9% and 32.2% at weeks 4, 8 and 52 respectively. LDL-C target was maintained in 81% and 69% of patients at week 8 and 52 respectively without drug related serious adverse events. Generic atorvastatin is safe and effective in usual clinical care setting.

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Tedeschi, R.E.; Martz, B.L.; Taylor, H.A.; Cerimelle, B.J. 1980: A long-term (9 years) clinical study of the safety and efficacy of probucol, and an analysis of morbidity and mortality rates La Nouvelle Presse Medicale 9(40): 3021-3027
Vetter, S.; Ruf, G.; Regourd, E.; März, W. 2004: The use of atorvastatin treatment in usual care environments: pooled analysis of six prospective, observational studies in 90,535 patients International Journal of Clinical Pharmacology and Therapeutics 42(8): 423-433
Yoshida, O.; Takeuchi, H.; Hida, S.; Tomoyoshi, T.; Arai, Y.; Okada, K.; Akino, H.; Isomatsu; Okabe, T.; Fukuyama, T. 1991: Clinical efficacy and safety of long-term administration of YM617 for urinary obstruction of the lower urinary tract Hinyokika Kiyo. Acta Urologica Japonica 37(4): 421-429
Rutstein, R.M.; Samson, P.; Fenton, T.; Fletcher, C.V.; Kiser, J.J.; Mofenson, L.M.; Smith, E.; Graham, B.; Mathew, M.; Aldrovani, G.; Rutstein, R.M.; Douglas, S.; Aldrovandi, G.; Kiser, J.; Fletcher, C.V.; Fenton, T.; Samson, P.; Graham, B.; Sprenger, H.L.; Mofenson, L.M.; Smith, E.; Purdue, L.; Kneut, C.; Ortiz, B.; Douglas, Q.; Petzold, E.; Myers, T.; Violari, A.; Gray, G.; Horga, M.; Schnittman, S.; Matthew, M.; Dieudonne, A.; Johnson, J.; Monti, L.; Bryson, Y.; Deville, J.G.; Nielsen-Saines, K.; Paul, M.; Hammill, H.; McMullen-Jackson, C.; Yogev, R.; Cagwin, E.; Williams, R.; Spector, S.A.; Viani, R.M.; Stangl, L.; Swetnam, J.; Wilson, J.; Donnelly, M.; Abrams, E.; Frere, M.; Calo, D.; Pelton, S.I.; McLaud, D.; Tucker, L.; Borkowsky, W 2015: Long-term safety and efficacy of atazanavir-based therapy in HIV-infected infants, children and adolescents: the Pediatric AIDS Clinical Trials Group Protocol 1020A Pediatric Infectious Disease Journal 34(2): 162-167
Piamsomboon, C.; Laothavorn, P.; Saguanwong, S.; Chatlaong, B.; Nasawadi, C.; Tanprasert, P.; Pongsiri, K. 2002: Efficacy and safety of atorvastatin 10 mg every other day in hypercholesterolemia Journal of the Medical Association of Thailand 85(3): 297-300
Miki, T. 2017: Efficacy and safety of long-term bisphosphonate treatment for osteoporosis Clinical Calcium 27(2): 239-246
Patrono, C. 2001: Efficacy and safety of aspirin in the long-term management of atherothrombosis Haematologica 86(11 Suppl 2: 19-21
Patrono, C. 2002: Efficacy and safety of aspirin in the long-term management of atherothrombosis Haematologica 87(1): 6-8
Penston, J.; Wormsley, K.G. 1990: Long-term maintenance therapy in duodenal ulcer. Efficacy and safety Fortschritte der Medizin 108(14): 282-286
Cooper, B.; Mohide, A.; Gilbert, S. 1989: Testing the use of color in a long-term care setting Dimensions in Health Service 66(6): 22; 24-26
Liping, Z.; Xiufang, L.; Tao, Y.; Baomin, Z.; Houshuai, T. 2018: Efficacy comparison of rosuvastatin and atorvastatin in the treatment of atherosclerosis and drug safety analysis Pakistan Journal of Pharmaceutical Sciences 31(5(Special): 2203-2208
Myburgh, D.P. 1990: Long-term efficacy and safety of sustained-release diltiazem in the treatment of hypertension South African Medical Journal 78(8): 456-457
DEN Dekker, W.K.; VAN Geuns, R.J.; Diletti, R. 2016: Long-term results of BVS implantation: a focus on safety and efficacy of the bioresorbable technology Minerva Cardioangiologica 64(4): 462-472
Kircik, L.H. 2017: Psoriasis Is a Chronic Disease: Long Term Efficacy and Safety of new Biologics Is Important Journal of Drugs in Dermatology: Jdd 16(8): S113-S114
McCue, J.D. 2000: Complicated UTI. Effective treatment in the long-term care setting Geriatrics 55(9): 48; 51
Nusbaum, N. 1997: Setting limits and long-term care of the frail elderly Southern Medical Journal 90(2): 256-260
Clarke, B.; McCormack, P. 2003: Prescribing practices in an Irish Long Term Care Setting Irish Medical Journal 96(7): 203-207
Shmidt, E.I.; Bilinskaia, M.A.; Belozerova, I.V.; Soldatov, D.G.; Dmitrieva, M.E. 2007: Long-term efficacy and safety of chondroitin sulphate (structum, France) in patients with coxarthrosis Terapevticheskii Arkhiv 79(1): 65-67
Katsiki, N.; Athyros, V.G.; Karagiannis, A.; Mikhailidis, D.P. 2011: Efficacy and safety of long-term ezetimibe/simvastatin treatment in patients with familial hypercholesterolemia International Angiology: a Journal of the International Union of Angiology 30(3): 295; Author Reply 296
Ohkubo, M.; Ishimitsu, T.; Kawaguchi, T.; Abe, M.; Yagi, S. 1993: Efficacy and safety of long-term erythropoietin therapy in chronic hemodialysis patients with renal anemia Nihon Jinzo Gakkai Shi 35(2): 171-177