Long-term efficacy and safety of chondroitin sulphate (structum, France) in patients with coxarthrosis
Shmidt, E.I.; Bilinskaia, M.A.; Belozerova, I.V.; Soldatov, D.G.; Dmitrieva, M.E.
Terapevticheskii Arkhiv 79(1): 65-67
2007
ISSN/ISBN: 0040-3660 PMID: 17385470 Document Number: 606641
Aim. To evaluate long-term therapeutic effect and safety of structum in patients with manifest coxarthrosis.Material and methods. Twenty patients with manifest coxarthrosis of degree I-III were given a 6 month structum course. Criteria of efficacy were Leken index, pain in the affected joints, nonsteroid anti-inflammatory drugs requirement, assessment of the efficacy by the patient and the doctor. Structum effects were studied with x-ray examination, CT, INC index. The assessment was made at baseline, after 3 and 6 month therapy and 6 12 and 18 months after the end of the study.Results. All the patients achieved positive results without side effects on coagulation.Conclusion. Structum is highly effective in patients with manifest osteoarthrosis of hip joints. Is modifies symptoms, has a potential chondroprotective effect, long-term aftereffect, no significant negative action of coagulation, is well tolerated.