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Succinic acid production using mobile bed of immobilized Actinobacillus succinogenes in alginate

Rotaru, R.; Kloetzer, L.ţa.; Galaction, A.-I.; Caşcaval, D.

Revista Medico-Chirurgicala a Societatii de Medici Si Naturalisti Din Iasi 115(1): 264-268

2011

ISSN/ISBN: 0048-7848
PMID: 21688587
Document Number: 650835
This work investigates the production of succinic acid by immobilized A. succinogenes cells, using a bioreactor with stirred/mobile bed of biocatalysts. The experiments have been carried out for different sizes of biocatalysts particle, under substrate and product inhibitory effects. The results indicated that the inhibitory effects could be diminished by cells immobilization, the substrate consumption rate increasing with the increase of biocatalyst particle size. Moreover, the biocatalysts can be used for many fermentation cycles.

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