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A case of effective weekly paclitaxel administration for advanced gastric cancer

Hasegawa, Y.; Kuroda, F.; Doi, T.; Takemura, S.; Nakamura, H.

Gan to Kagaku Ryoho. Cancer and ChemoTherapy 38(4): 655-657

2011

ISSN/ISBN: 0385-0684
PMID: 21498999
Document Number: 648167
A 74-year-old man was admitted to our hospital with severe anemia. Endoscopic examination revealed a type 3 advanced gastric cancer. Abdominal computed tomography revealed massive lymph node metastasis(N3). We performed distal gastrectomy(noncurative resection)because anemia had progressed. After operation, we administered S-1/CDDP combination chemotherapy. Although he received two courses of S-1/CDDP, renal dysfunction was found. Afterwards a rise in tumor marker(CEA)occurred, so we changed to chemotherapy with weekly paclitaxel. Abdominal computed tomography then revealed a complete response(CR)after the chemotherapy was completed. At present, 7 years after the operation, the patient remains free of a rise in tumor markers and presents no evidence of a recurrence.

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