Weekly administration of paclitaxel as a second-line chemotherapy for advanced and recurrent gastric cancer
Makari, Y.; Fujiwara, Y.; Yasuda, T.; Takiguchi, S.; Kimura, Y.; Yano, M.; Monden, M.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 31(4): 609-611
2004
ISSN/ISBN: 0385-0684 PMID: 15114710 Document Number: 580870
Chemotherapy with TS-1 has recently become the first-line chemotherapy for recurrent and unresectable gastric cancer in Japan. Therefore, the establishment of a second-line chemotherapy is needed for cases that show resistance and aberrant effect to TS-1. In this study, 7 patients were treated with weekly administrations of paclitaxel after TS-1 treatment. We assessed the therapeutic effect and feasibility of chemotherapy with weekly administration of paclitaxel. Our results showed that weekly administration of paclitaxel could be a promising regimen as a second-line chemotherapy after TS-1.