New polymer-drug systems based on natural and synthetic polymers
Racoviţă, S.; Vasiliu, S.; Foia, L.
Revista Medico-Chirurgicala a Societatii de Medici Si Naturalisti Din Iasi 114(2): 484-489
2010
ISSN/ISBN: 0048-7848 PMID: 20700991 Document Number: 647643
The great versatility of polymers makes them very useful in the biomedical and pharmaceutical fields. The combination of natural and synthetic polymers leads to new materials with tailored functional properties. The aim of this work consists in the preparation of new drug delivery system based on chitosan (natural polymer) and polybetaines (synthetic polymers), by a simple process, well known in the literature as complex coacervation methods. Also, the adsorption and release studies of two antibiotics as well as the preservation of their bactericidal capacities were performed.