Thermosensitive polymers in drug form technology. II. Possibilities of use of thermosensitive polymers as active substance carriers
Karolewicz, B.; Pluta, J.
Polimery W Medycynie 38(1): 15-26
2008
ISSN/ISBN: 0370-0747 PMID: 18661703 Document Number: 618796
Thermosensitive drug delivery can be used as substances carriers, which are applied in oral system, vaginal systems of release, applied on skin, the rectal, nasal, passed to eyes and parenteral. Sol-gel transition of the prepared formulations at physiological temperature ranges of the body makes possible their application in the liquid state and subsequent gelification in situ providing a prolonged release of the active substance at the application site.