Top Abstract Purchase Related
Home
>
Node
>
Subnode

Molecular genetic studies of the susceptibility of epidemic influenza A (H1N1) virus strains isolated in the 2006-2009 seasons in Russia to oseltamivir (Tamiflu)

Beliakova, N.V.; Al'khovskiĭ, S.V.; Shevchenko, E.S.; Prilipov, A.G.; Abramov, D.D.; Kolobukhina, L.V.; Merkulova, L.N.; Trushakova, S.V.; Burtseva, E.I.

Voprosy virusologii 55(5): 10-13

2010

ISSN/ISBN: 0507-4088
PMID: 21260988
Document Number: 645583
Oseltamivir (Tamiflu) is recommended by WHO experts as a drug to treat and prevent of influenza and to create stocks if its new pandemic variant occurs. The susceptibility of influenza viruses to oseltamivir was studied by polymerase chain reaction-based techniques detecting specific mutations in the neuraminidase gene. The increase in the number of oseltamivir-resistant influenza viruses, isolated from the Russian Federation, with type 1 neuraminidase H274Y mutation from 49% (2007-20008) to 92% (2008-2009) did not depend on the frequency of oseltamivir use. Full correlation of the results obtained by various techniques allows them to be used to monitor the susceptibility of influenza viruses to oseltamivir.

Document emailed within 1 workday
Secure & encrypted payments

Kolobukhina, L.V.; Merkulova, L.N.; Burtseva, E.I.; Isaeva, E.I.; Shchelkanov, M.Iu.; Beliakova, N.V.; Grebennikova, T.V.; Polikushina, O.E.; Rotanov, M.; Malyshev, N.A.; L'vov, D.K. 2008: Efficacy of ozeltamivir (Tamiflu) in adult influenza on the epidemic rise of morbidity in Russia in the 2006-2007 season Voprosy Virusologii 53(4): 23-26
Sokolov, M.I.; Podcherniaeva, R.Ia.; Parasiuk, N.A.; Miasnikova, I.A.; Men'shikh, L.K. 1970: Genetic markers and their variability in influenza viruses isolated from the 1968-1969 influenza epidemic. I. The biologic properties of strains of variety A2 (Hong Kong) 1-68 Voprosy Virusologii 15(6): 677-680
Ivanova, V.T.; Burtseva, E.I.; Slepushkin, A.N.; Oskerko, T.A.; Zagorskaia, I.V.; Kolobukhina, L.V.; Feodoritova, E.L. 2003: Spread and properties of epidemic influenza A and B virus strains accountable for morbidity in Russia during 1999-2002 Voprosy virusologii 48(4): 11-15
Shikov, A.N.; Sementsova, A.O.; Demina, O.K.; Sergeev, A.A.; Berillo, S.A.; Sergeeva, E.I.; Vinokurova, A.V.; Ishenina, A.V.; Ternovoĭ, V.A.; Agafonov, A.P.; Drozdov, I.G. 2011: Genetic variability of isolates of pandemic influenza a virus H1N1 isolated in Russia in 2009 Molekuliarnaia Genetika Mikrobiologiia i Virusologiia 4: 23-29
Klimov, A.I.; Tikhonova, A.M.; Gorodkova, N.V.; Herrman, B.; Döhner, L.; Ghendon, Y.Z. 1984: Genome analysis of epidemic influenza virus strains isolated in 1979-1983 Acta Virologica 28(6): 479-486
Shilov, A.A.; Kozlov, I.V.; Chaĭka, O.V.; Kurmanova, A.G.; Zhdanov, V.M. 1987: Genetic variability of epidemic strains of influenza virus serotypes H1N1 and H3N2 during antigenic drift Voprosy Virusologii 32(4): 419-429
Lobodzińska, M.; Chomik, M.; Albin, M.; Zakstelskaya, L.Y.; Shenderovich, S.F.; Molibog, E.V. 1983: Comparison of biological properties of A(H1N1) influenza virus strains isolated in 1947 and during the epidemic of 1977 Archivum Immunologiae et Therapiae Experimentalis 31(1): 85-91
Petrova, I.D.; Seregin, S.V.; Petrov, V.S.; Vyshemirskiĭ, O.I.; Kuzina, I.I.; L'vov, D.K.; Samokhvalov, E.I.; Tiunikov, G.I.; Gutorov, V.V.; Iashina, L.N.; Netesov, S.V. 2003: Genetic characteristics of the S-segment of RNA from two strains of the Crimean-Congo hemorrhagic fever virus isolated in the south of Russia and in Uzbekistan Voprosy Virusologii 48(2): 8-11
Semkow, R.; Zgorzelska, K.; Brydak, L. 1971: Studies on the adaptation of freshly isolated strains of influenza virus. II. Endogenous respiration of the organs in virus-infected mice Medycyna Doswiadczalna i Mikrobiologia 23(2): 141-146
Ivanova, V.T.; Matiushina, R.O.; Slepushkin, A.N.; Burtseva, E.I.; Oskerko, T.A.; Shevchenko, E.S.; Trushakova, S.V.; Kurochkina, I.E.; Zagorskaia, I.N.; Cherkasov, E.G.; Merkulova, L.N.; Feodoritova, E.L. 2008: Epidemic strains influenza viruses A and B in the 2005-2006 season in Russia Voprosy virusologii 53(4): 13-18
Korchanova, N.L.; Simanovskaya, V.K.; Sominina, A.A.; Gordon, M.A.; Goloveshkina, T.N.; Kuznetsova, E.V. 1983: Comparative studies on influenza B virus. I. Biological properties and polypeptide composition of strains isolated in different years Acta Virologica 27(5): 377-384
Yanagita, M.; Kuwamura, Y.; Kinoshita, S.; Nakajima, T.; Tomizawa, S.; Ozawa, T. 2014: Mutations in the Neuraminidase Gene of the Epidemic Influenza Virus Strain Isolated in the 2012-2013 Season and Improvement of a PCR Assay for the Detection of Influenza Virus Rinsho byori. Japanese journal of clinical pathology 62(10): 937-941
L'vov, D.K.; Al'khovskiĭ, S.V.; Shchelkanov, M.I.; Deriabin, P.G.; Gitel'man, A.K.; Botikov, A.G.; Aristova, V.A. 2014: Genetic characterisation of Powassan virus (POWV) isolated from Haemophysalis longicornis ticks in Primorye and two strains of Tick-borne encephalitis virus (TBEV) (Flaviviridae, Flavivirus): Alma-Arasan virus (AAV) isolated from Ixodes persulcatus ticks in Kazakhstan and Malyshevo virus isolated from Aedes vexans nipponii mosquitoes in Khabarovsk kray Voprosy Virusologii 59(5): 18-22
Reizin, F.N.; Chumakov, M.P.; Martyanova, L.I. 1990: Heterogeneity of influenza B virus strains isolated in a local area of the disease during an influenza outbreak Acta Virologica 34(2): 178-183
Higashihara, M. 1975: Studies on genetic recombinants of influenza virus: fundamental studies on recombinant influenza-virus vaccines Kitasato Archives of Experimental Medicine 48(4): 183-188
Markushin, S.G.; Akopova, I.I.; Koptiaeva, I.B.; Tsfasman, T.M.; Gendon, I.Z. 2006: Molecular mechanisms of reversions to the ts+ -phenotype of cold-adapted influenza virus a strains--attenuation donors for live influenza reassortant vaccines Voprosy Virusologii 51(5): 17-22
Prahoveanu, E.; Boeru, V.; Teodosiu, O.; Petrescu, A. 1979: Susceptibility of irradiated mice to inoculation with two influenza virus strains Virologie 30(1): 29-35
Aleksandrova, G.I.; Dekhtyareva, N.I.; Medvedeva, T.E.; Shneider, M.A. 1982: Correlation between reproductive and interfering activities of epidemic and thermosensitive influenza virus strains Acta Virologica 26(3): 113-118
Popa, L.M.; Mihail, A.; Burducea, O.; Repanovici, R. 1976: Isolation, purification and characterization of polypeptides of influenza and parainfluenza viruses. Note III. Polypeptides of three influenza virus strains isolated in Romania Virologie 27(3): 187-191
Blokha, V.V.; Iamnikova, S.S.; Karpovich, L.G.; Iakhno, M.A.; Zakstel'skaia, L.I. 1985: Radioimmunological study of the antigenic conformity of the hemagglutinins of vaccinal and epidemic strains of influenza virus Voprosy Virusologii 30(1): 24-27