Risk factors associated with preeclampsia: case-control study
Morgan-Ortiz, F.; Calderón-Lara, S.A.; Martínez-Félix, J.ús.I.; González-Beltrán, A.; Quevedo-Castro, E.
Ginecologia y Obstetricia de Mexico 78(3): 153-159
2010
ISSN/ISBN: 0300-9041 PMID: 20939218 Document Number: 644563
In women, breast cancer causes over one million new cases each year, of which about half occur in industrialized countries, however, is in developing countries like ours, where most deaths due to this cause. Currently, the breast cancer is the leading cause of death from malignancy in women over 25 years. The conclusions of the Third Review of the National Consensus on Diagnosis and Treatment of Breast Cancer are a guide for oncologists, mastologists and the medical community in general. This review involved more than 50 physicians with national recognition of all institutions and specialties related to this disease, in order to contribute their knowledge. Preeclampsia is one of the most frequent and serious complication of pregnancy characterized by systemic perfusion reduction generated by vasospasm and activation of coagulation systems. To evaluate the association between preeclampsia sociodemographics and obstetrics antecedents. An unmatched case-control study was carried out in which all the clinical registries of patients with preeclampsia (cases: n = 196) assisted in the period 2003-2007 in the Hospital Civil of Culiacan, Sinaloa State of Mexico were analyzed. As controls the clinical registries of patients assisted during the same period were selected at random but that they didn't show up preeclampsia (n = 470). The association of preeclampsia with socioeconomic level, tobacco use, alcohol use, gynecologic and obstetric antecedents (sexual partners, pregnancies, deliveries and abortions number, prenatal control, contraceptive method) and previous pregnancy with preeclampsia were analyzed. There were not association between tobacco use (OR: 3.05; 95% CI: 0.81-11.48), beginning of sexual activity (p = 0.1509), number of sexual partners (OR: 1.23; 95% CI: 0.83-1.83; p = 0.3009) and sexual cohabitation less than 12 months (OR: 0.90; 95% CI: 0.63-1.27). The alcoholism (OR: 5.77; 95% CI: 1.48-22.53), socioeconomic level (p < 0.05), pregnancy previous with preeclampsia (RM:14.81; 95% CI: 1.77-123.85; p = 0.0006) were associated with preeclampsia. There were differences in the use of the contraceptive method between groups (p < 0.005). Preeclampsia was significantly associated with the alcoholism, low socioeconomic level and pregnancy previous with preeclampsia.