Multiple myeloma and occupational risk factors: a case-control study
Discalzi, G.; Cioci, I.; Ganio, L.; Ponzetti, C.; Coscia, G.
La Medicina del Lavoro 82(3): 248-252
1991
ISSN/ISBN: 0025-7818 PMID: 1795669 Document Number: 376951
In order to identify possible relationships between multiple myeloma (MM) and occupational factors, a hospital-based case control type study was carried out on 94 cases of MM and on 188 controls matched for sex, age (S.D. = 2 years) and area of residence, suffering from orthopaedic trauma and free of chronic/degenerative or tumoral diseases. All jobs done for at least a year in a period of 5-30 years before diagnosis were considered. Statistical analysis showed a significant correlation between MM and agricultural work (OR 1.82; I.C. 95% 1.03-3.25), which agrees with the data in the literature. The etiopathogenetic hypotheses reported in the literature are discussed and proposals for further research are made.