Cytotoxic activity of epsilon-aminocaproylamino acids in breast cancer MCF-7 and fibroblast cell lines
Midura-Nowaczek, K.; Markowska, A.; Krajewska, D.; Wołczyński, S.ła.
Acta Poloniae Pharmaceutica 67(2): 201-204
2010
ISSN/ISBN: 0001-6837 PMID: 20369798 Document Number: 644397
The effect of H-EACA-L-Cys(S-Bzl)-OH, H-EACA-L-Leu-OH, H-EACA-L-Nle-OH and EACA on the viability of MCF-7 and fibroblast cells was examined. The antibacterial activity of these compounds was also tested. H-EACA-L-Leu-OH and H-EACA-L-Nle-OH showed cytotoxic activity against MCF-7 and fibroblast cell lines, particularly in the highest studied 20 mM concentration. None of the examined dipeptides showed antibacterial activity.
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