Extracranial meningioma: morphological and histogenetical aspects and relations with perineurioma
Shelekhova, K.V.
Arkhiv Patologii 72(3): 12-16
2010
ISSN/ISBN: 0004-1955 PMID: 20734826 Document Number: 642739
The clinicomorphological, immunohistochemical, and ultrastructural characteristics of 11 cases of extracranial meningioma versus 79 soft tissue perineuriomas were studied. There were significant similarities (cell morphology, immunoprofile, ultrastructural features of perineurial differentiation) of both entities. Considering the point of view that arachnoid and perineurial cells are anatomically, embryologically, and functionally related, it is most possible that extracranial meningiomas may be derived from perineurial cells (or their progenitor cell) rather than from displaced arachnoid cells.