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Overlap syndrome: autoimmune hepatitis with primary biliary cirrhosis

Arulprakash, S.; Sasi, A.D.; Bala, M.R.; Pugazhendhi, T.; Kumar, S.J.

Journal of the Association of Physicians of India 58: 455-456

2010

ISSN/ISBN: 0004-5772
PMID: 21121216
Document Number: 640791
"Overlap syndrome" is used to describe variant forms of autoimmune hepatitis (AIH) which present with characteristics of AIH and primary biliary cirrhosis (PBC) or primary sclerosing cholangitis (PSC). Patients with overlap syndromes present with both hepatitic and cholestatic serum liver tests and have histological features of AIH and PBC or PSC. AIH-PBC is the most common form of overlap syndrome, affecting almost 10% of adults with AIH or PBC. Transitions from PBC to AIH-PBC overlap syndrome have also been reported. Overlap syndromes show a progressive course without treatment, and therapy is empiric. Ursodeoxycholic acid is usually combined with immunosuppressive therapy but end-stage disease requires liver transplantation. We report a case of AIH/PBC overlap with relevant discussion of literature.

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Serghini, M.; Haddad, W.; Karoui, S.; Ben Mustapha, N.; Kallel, L.; Fekih, M.; Boubaker, J.; Filali, A. 2012: Overlap syndrome of primary biliary cirrhosis and autoimmune hepatitis La Tunisie Medicale 90(10): 741-743
Abbasciano, V.; Trevisani, L.; Di Todaro, F.; Guglielmini, C.; Marzola, A.; Sartori, S.; Salemi, A. 2006: Primary biliary cirrhosis and autoimmune hepatitis overlap syndrome. An early case Recenti Progressi in Medicina 97(1): 28-31
Ozaslan, E.; Efe, C.; Akbulut, S.; Purnak, T.; Savas, B.; Erden, E.; Altiparmak, E. 2010: Therapy response and outcome of overlap syndromes: autoimmune hepatitis and primary biliary cirrhosis compared to autoimmune hepatitis and autoimmune cholangitis Hepato-Gastroenterology 57(99-100): 441-446
Renner, E.L. 1994: Treatment of autoimmune chronic active hepatitis and of primary biliary cirrhosis Schweizerische Medizinische Wochenschrift 124(12): 495-501
Patel, N.; Amarapurkar, D.; Amarapurkar, A. 2005: Primary biliary cirrhosis and autoimmune hepatitis switch over: report of 2 cases Tropical Gastroenterology: Official Journal of the Digestive Diseases Foundation 26(3): 136-138
Manohar, A.; Ca, J.; Hn, N.K. 2020: An Overlap of Primary Biliary Cirrhosis and Sarcoidosis Journal of the Association of Physicians of India 68(1): 79
Vella, F.Saverio.; Simone, B.; Orlando, P.; Simone, O.; Antonaci, S. 2004: Chronic hepatitis C/autoimmune hepatitis overlap syndrome: report of two cases Recenti Progressi in Medicina 95(10): 472-475
Antonaci, S.; Giannelli, G.; Simone, B.; Vella, F.S. 2005: Syndrome of overlap: Chronic hepatitis C/autoimmune hepatitis: fact or fancy? Recenti Progressi in Medicina 96(1): 27-31
Chen, C.Y.; Lu, C.L.; Chiu, C.F.; Chang, F.Y.; Lee, S.D. 1997: Primary biliary cirrhosis associated with mixed type autoimmune hemolytic anemia and sicca syndrome: a case report and review of literature American Journal of Gastroenterology 92(9): 1547-1549
Garassini Serra, M.A.; Garassini Chávez, M.E. 1995: Liver autoimmune diseases. II. Primary biliary cirrhosis G.E.N 49(1): 82-89
Shoenfeld, Y. 1992: Primary biliary cirrhosis and autoimmune rheumatic diseases: prediction and prevention Israel Journal of Medical Sciences 28(2): 113-116
Calès, P.; Calot, M.; Voigt, J.J.; Oksman, F.; Cassigneul, J.; Vinel, J.P.; Pascal, J.P. 1983: Familial autoimmune pathology comprising 2 cases of primary biliary cirrhosis Gastroenterologie Clinique et Biologique 7(10): 777-784
Pollak, C.; Minar, E.; Dragosics, B.; Marosi, L. 1985: Primary biliary cirrhosis and scleroderma: long-term benign course of a complex autoimmune disease Leber Magen Darm 15(2): 85-89
Kong, F.; Li, J-Xin.; Li, P.; Li, Y-Zhe.; Zhang, F-Chun.; Zhang, J. 2013: Association of TNFSF4 polymorphisms with susceptibility to primary Sjögren's syndrome and primary biliary cirrhosis in a Chinese Han population Clinical and Experimental Rheumatology 31(4): 546-551
Mosimann, F.; Fontolliet, C.; Ruegsegger, C.H.; Bonard, E.C. 1984: Granulomatous hepatitis and portal hypertension. Sarcoidosis? Primary biliary cirrhosis? Brucellosis? Schweizerische Rundschau für Medizin Praxis 73(33): 1019-1022
Labayle, D.; Bossuet, P.; Brunaud, M.D.; Courpotin, G.; Etienne, J.P. 1980: Primary biliary cirrhosis or chronic active hepatitis. Observations on five unclassified cases Gastroenterologie Clinique et Biologique 4(12): 848-853
Leclech, C.; Friedel, J.; Jeandel, C.; Lux, C.; Heid, E. 1987: Reynolds' syndrome: the combination of scleroderma of CREST syndrome type and primary biliary cirrhosis Annales de Dermatologie et de Venereologie 114(6-7): 857-859
Thorel, J.B.; Deshayes, P. 1981: Digital necrosis disclosing Reynolds' syndrome (primary biliary cirrhosis and scleroderma) with Gougerot-Sjögren syndrome La Nouvelle Presse Medicale 10(27): 2295-2296
Lüders, C.J.; Kruck, P.; Henning, H.; Look, D. 1974: Histological and clinical studies on the differential diagnosis of the aggressive chronic hepatitis and primary biliary liver cirrhosis Zeitschrift für Gastroenterologie 12(6): 467-484
Ahlqvist, J. 1980: Can endocrine factors influence pathogenetic mechanisms in chronic active hepatitis (CAH) and primary biliary cirrhosis (PBC)? a hypothesis Hepato-Gastroenterology 27(1): 64-67