Lithogenicity of bile and serum lipoproteins (A) in cholelitiasis in women
Grigor'eva, I.N.; Nikitenko, T.M.; Tikhonov, A.V.
Eksperimental'naia i Klinicheskaia Gastroenterologiia 3: 4-8
2009
ISSN/ISBN: 1682-8658 PMID: 19938284 Document Number: 637593
Blood serum Lp (a) level's increasing accompanied significant rising of gallbladder bile lithogenicity in the women with gallstone disease (GSD) with verified cholesterol gallstones. Apolipoprotein (a) (Apo (a)) isoforms B, S1 (most atherogenic) frequency in the women with GSD was significantly higher, and isoforms Apo (a) 0, S4 - significantly lower than in the women in control group without GSD. Gallbladder bile was significantly more lithogenic in the women with GSD who had Apo (a) B and S1 isoforms than in women with GSD with isoforms Apo (a) 0 and S4.