Kinetic features of ascites and solid Ehrlich tumors
Moiseenko, V.M.; Chudenko, V.A.; Stukov, A.N.; Anikin, I.V.; Pozharisskiĭ, K.M.; Maksimova, N.A.
Voprosy Onkologii 55(5): 598-602
2009
ISSN/ISBN: 0507-3758 PMID: 20020656 Document Number: 634455
Such biological parameters as tumor volume, Ki-67 and p53, which characterize the development of ascites and solid tumor of Ehrlich were evaluated. The kinetic curve of growth of ascites tumor was S-shaped (Gomperts) while that of the solid one--cubic (Speer-Retsky). Ki-67 expression level was found to be in cyclic correlation with duration (3 and 6 day intervals) which might be worth considering when working out therapeutic procedure. Moreover, no increase in cell death was observed when tumor growth slowed down.