Some kinetic characteristics of cervical cancer
Zharinov, G.M.; Pozharisskiĭ, K.M.; Vinokurov, V.L.; Neklasova, N.I.; Mironovskaia, N.V.; Kuznetsova, M.E.; Tarkova, A.B.
Voprosy Onkologii 55(2): 196-200
2009
ISSN/ISBN: 0507-3758 PMID: 19514375 Document Number: 633271
Proliferation parameters such as mitotic index, tumor growth rate and cell loss were identified in 1,048 squamous cervical carcinoma patients treated at the Center's Clinic (1951-1996). Mitotic indices ranged 0.2-5.1% (average 1.13 +/- 0.03%), Ki-67--4.1-97.8% (average 49.97 +/- 3.02%). A direct and significant correlation between the two latter parameters was established. Cell loss levels ranged 59-99.9% (average 97.2 +/- 0.002%). Our results suggest that the correlation between tumor growth rate and cell loss might be of the utmost importance among the other prognostic factors.