Dietary intervention after definitive therapy for localized prostate cancer: results from a pilot study
Parsons, J.K.; Newman, V.A.; Mohler, J.L.; Pierce, J.P.; Flatt, S.; Messer, K.; Marshall, J.
Canadian Journal of Urology 16(3): 4648-4654
2009
ISSN/ISBN: 1195-9479 PMID: 19497171 Document Number: 630351
Diet has been linked to prostate cancer risk. Dietary modification may inhibit prostate cancer progression. As part of a randomized trial, we analyzed the effect of a diet based intervention on 25 prostate cancer patients who had previously undergone surgery or radiation. In the intervention arm, vegetable intake increased (p < 0.05), fat intake decreased (p < 0.05), and mean plasma levels of ss-carotene and total carotenoids increased (p < 0.05). In the control arm, there were no significant changes in diet or blood carotenoids. These data support the feasibility of studying dietary interventions as salvage or adjuvant therapy after surgery or radiation for localized prostate cancer.