Measles-specific neutralizing antibodies in rural Mozambique: seroprevalence and presence in breast milk
Mandomando, Iácio.M.; Naniche, D.; Pasetti, M.F.; Vallès, X.; Cuberos, L.; Nhacolo, A.; Kotloff, K.L.; Martins, H.; Levine, M.M.; Alonso, P.
American Journal of Tropical Medicine and Hygiene 79(5): 787-792
2008
ISSN/ISBN: 0002-9637 PMID: 18981523 Document Number: 623955
In Mozambique, as in many sub-Saharan countries, measles remains a public health problem. We conducted cross-sectional surveys in which we assessed measles-specific antibodies in serum and breast milk by plaque reduction neutralization (PRN) assay and measles secretory IgA in breast milk by ELISA. A total of 151 persons <1 month to 23 years of age were surveyed; 81 (53.6%) of 151 had PRN titres equal to or above the protective level (>=200 mIU/ml).