Advances in protein therapeutics
Woodnutt, G.; Violand, B.; North, M.
Current Opinion in Drug Discovery and Development 11(6): 754-761
2008
ISSN/ISBN: 1367-6733 PMID: 18946840 Document Number: 621877
This review summarizes recent advances in the discovery and development of novel protein therapeutics. The most advanced technology platforms currently available are highlighted and examples where novel protein scaffolds have been successfully applied to identify clinical candidates are provided. This review also examines the progress of these molecules in the clinic and discusses the advantages and disadvantages of these approaches over traditional methods.