Heat shock protein in male infertility: advances in studies
He, B.; Li, Q.; Zhuo, H.
Zhonghua Nan Ke Xue 19(5): 464-467
2013
ISSN/ISBN: 1009-3591 PMID: 23757974 Document Number: 668926
Heat shock protein (HSP) is a group of evolutionarily highly conserved cell chaperone proteins involved in the processes of molecular chaperone, cytoprotection, anti-apoptosis and immunoregulation. Recent studies found that HSP is also involved in spermatogenesis, sperm capacitation and fertilization, which play a significant role in male reproduction. Therefore, further studies on the action mechanisms of HSP in male infertility may offer a new insight into the management of the problem.