Studies on chemical constituents in roots and rhizomes of Notopterygium incisum
Zhang, P.; Yang, X.-W.
Zhongguo Zhong Yao Za Zhi 33(24): 2918-2921
2008
ISSN/ISBN: 1001-5302 PMID: 19294850 Document Number: 621818
To study the chemical constituents in the roots and rhizomes of Notopterygium incisum. The chemical constituents were isolated by various column chromatographic methods and structurally elucidated by NMR and MS evidences. Twenty-four compounds were obtained and identified as isocalamenediol (1), pregnenolone (2), beta-sitosterol (3), bergapten (4), bergaptol (5), cnidilin (6), isoimperatorin (7), bergamottin (8), demethylfuropinnarin (9), nodakenetin (10), 7'-O-methylnotoptol (11), notopterol (12), notoptol (13), pabulenol (14), phenethylferulate (15), p-hydroxyphenethyl anisate (16), trans-ferulic acid (17), nodakenin (18), sucrose (19), 2-methoxy-4-(3-methoxy-1-propenyl)-phenol (20), 3, 4, 5 trimethoxy-trans-cinnamic acid (21), p-methoxycinnamic acid (22), 4-acetoxy-3-methoxy-trans-cinnamic acid (23), and p-hydroxy-trans-cinnamic acid (24). Compounds 1, 14, 20-24 were isolated from the roots and rhizomes of N. incisum for the first time. Compounds 1 and 14 are sesquiterpenoid and coumarin, respectively, and 20-24 were phenylpropanoid compounds.