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Chemical constituents from roots of Platycodon grandiflorum

Li, L.-J.; Liu, Z.-H.; Chen, Y.; Tian, J.-K.

Zhongguo Zhong Yao Za Zhi 31(18): 1506-1509

2006

ISSN/ISBN: 1001-5302
PMID: 17144467
Document Number: 601243
To study the chemical constituents from roots of Platycodon grandiflorum. Column chromatography (silica gel, macroporous resin, sephadex LH - 20 and the preparative RP - HPLC were used to isolate the constituents. Their structures were elucidated by physical and spectral data. Eight compounds were isolated and identified as tangeritin (1), 3-O-beta-D-glucopyranosylplatycodigenin methyl ester (2), 3-O-beta-D-glucopyranosylplaticogenic acid A lactone (3), 3-O-beta-D-glucopyranosylplatycodigenin (4), deapio-platyconic acid A lactone (5), deapio-platycodin-D (6), platycoside-G1 (7) and platycoside-E (8). Compounds 1,3 and 5 were isolated from this plant for the first time.

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