Current status of the diagnosis and treatment of Leydig cell testicular tumor. Report of two cases
Pastor Navarro, Héctor.; Donate Moreno, Mía.J.; Carrión López, P.; Pastor Guzmán, Jé.M.; Segura Martín, M.; Lorido Cortés, Mía.M.; Cañamares Pabolaza, L.; Ruíz Mondéjar, R.; Salinas Sánchez, A.S.; Virseda Rodríguez, J.A.
Archivos Espanoles de Urologia 61(1): 27-33
2008
ISSN/ISBN: 0004-0614 PMID: 18405025 Document Number: 620783
To review the current diagnosis and treatment of Leydig cell testicular tumors, with special attention to conservative treatment. We report two cases of Leydig cell tumor in young adults, diagnosed two years after the appearance of bilateral gynecomastia as first clinical symptom. One year and eight months after orchyectomy, respectively, clinical symptoms completely disappear in the first case and significantly improved in the second. Around 10% of the cases, and only in adult patients, these tumors may be malignant, being radical orchyectomy the treatment of choice, although conservative surgery may be performed. Independently of the operation, follow-up must be prolonged.