Treatment strategy for stage i testicular germ cell tumor
Nakai, Y.; Nagahara, A.; Uemura, M.; Takayama, H.; Nonomura, N.
Hinyokika Kiyo. Acta Urologica Japonica 58(12): 715-720
2012
ISSN/ISBN: 0018-1994 PMID: 23328172 Document Number: 657348
Most stage I testicular germ cell tumors are curable by orchiectomy alone. However, some tumors recur and require subsequent treatment. The point for the management of stage I testicular germ cell tumors is how to reduce the recurrence rate by appropriate adjuvant treatment with less adverse events. The strategy for stage I seminoma and stage I nonseminoma is different. The adjuvant treatment options include radiotherapy and 1-2 courses of carboplatin for seminoma and retroperitoneal lymph node dissection (RPLND) and 1-2 courses of bleomycin, etoposide and cisplatin chemotherapy for nonseminoma. This review discusses recent literature on adjuvant treatment and updates the consensus for the management of stage I testicular germ cell tumor.