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Biological activity of Ungernia victoris extract in the Escherichia coli CaCl2-transformation system in the presence of calcium channel modulators

Miriuta, A.I.; Pererva, T.P.

Tsitologiia i Genetika 42(4): 45-49

2008

ISSN/ISBN: 0564-3783
PMID: 19140430
Document Number: 616971
Furosemid and verapamil appear to have an effect on the yield of E. coli plasmid transformants according to their properties as calcium channel regulators in eukaryotes. It means that furosemid stimulates and verapamil inhibits transforming DNA penetration into competent cell. PHB/Ca2+ polyP complex does not function only as a channel for transforming DNA penetration but appears to be one of the targets for transformation blocking U. victoris extract.

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